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Mecanismo de ação

GAD - GLUTAMATO DESCARBOXILASE
Enzima que catalisa a descarboxilação do glutamato para formar o GABA.

Imagem adaptada de Snead, O.; Gibson, K. (2005). γ-Hydroxybutyric Acid. New England Journal of Medicine, 352(26): 2721-2732.

Referências:

[5] Snead, O.; Gibson, K. (2005). "γ-Hydroxybutyric Acid. New England Journal of Medicine", 352(26): 2721-2732.

[6] Schep, L. J., et al. (2012). "The clinical toxicology of gamma-hydroxybutyrate, gamma-butyrolactone and 1,4-butanediol. Clinical Toxicology", 50(6): 458-470.

[7] Benarroch, E. (2009). "γ-Hydroxybutyric acid and its relevance in neurology". Neurology, 72(3): 282-286.

2016 © by Luis Melo| Teresa Freitas | Tiago Ferreira 

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